Clomid is a mixed estrogen agonist/antagonist (activator/blocker)
which, when bound to the estrogen receptor, puts it in a somewhat
different conformation (shape) than does estradiol. The estrogen
receptor requires binding of an estrogen or drug at its binding
site and also the binding of any of several cofactors at different
sites. Without the binding of the cofactor, the estrogen receptor
is inactive. Different tissues use different cofactors. Some of
these cofactors are able to bind to the estrogen receptor/Clomid
complex, but others are blocked due to the change in shape. The
result is that in some tissues Clomid acts as an antagonist - The
cofactor used in that tissue cannot bind and so the receptor
remains inactive - And in others Clomid acts as an agonist
(activator), because the cofactors used in that tissue are able to
CAS No: 50-41-9
Einecs No: 200-035-3
Appearance: White power; Odourless.
Steroids Hormone Clomiphene Citrate/Clomid powders/CAS No: 50-41-9
Clomid is the anti-estrogen of choice for improving recovery of
natural testosterone production after a cycle, improving
testosterone production of endurance athletes, and is also
effective in reducing risk of gynecomastia during a cycle employing
|Test Items||Specification||Test Results|
|Appearance||White or off-white powder||white powder|
|Water||Not more than 1.0%||0.38%|
|Heavy water||Not more than 0.002%||Conforms|
|Related impuries||Related compound A:Not more than 2.0%||0.86%|
|Individual:Not more than 0.5%||0.38%|
|Conclusion||This batch is complies with USP 32.|
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